Newsletter

ZIROXIM 250 Cp.

B / 20Cp / 2BL
$8.00

COMPOSITION
Cefuroxime (DCI) 250 mg

INDICATIONS
• They carry antibacterial activity.
• They are limited to mono or polymicrobial infections due to susceptible organisms when these infections allow oral antibiotics (excluding subarachnoid locations).
- Tonsillitis and pharyngitis: Due to its characteristics, Ziroxim should be reserved for recurrent tonsillitis and (or) chronic tonsillitis. Penicillin prescribed for 10 days, remains the treatment of choice for streptococcal pharyngitis;
- Sinusitis in adults;
- Acute otitis of the middle ear.
Lower respiratory tract infections:
- Acute and chronic bronchitis in adults;
- Bacterial Pneumonia in adults.

CONTRAINDICATIONS
- Known allergy to the cephalosporin group of antibiotics.
- Women in the first trimester of pregnancy or nursing.

WARNINGS AND PRECAUTIONS
- The occurrence of an allergic manifestation require stopping treatment.
- The prescription of cephalosporins requires discovery.
- The pharmaceutical form is not suitable for treating children under 5 years.
- In patients with renal insufficiency, dosage adjustment based on the creatinine clearance or creatinine.
• Combinations requiring precautions for use:
- Antihistamines H2: ranitidine and / or antacids (sodium bicarbonate) increase in gastric pH resulting in decreased bioavailability.
Taking medications that reduce stomach acid away from the drug (more than 4 hours, if possible).
Can cause:
- Gastrointestinal disorders: diarrhea, nausea, vomiting.
- Allergic reactions: rash, hives, fever, serum sickness.
- Rare cases of headache.
- Events Blood.
- Transient elevations of transaminases AST and ALT and LDH.
- Nephrotoxicity.

DOSAGE AND ADMINISTRATION
ENT Infection:
- Tonsillitis, pharyngitis:
Adult: 500 mg / day in 2 doses.
Children over 5 years: 20 mg / kg / day in 2 divided doses without exceeding the adult dosage is 500 mg / day in 2 doses.
- Sinusitis:
Adult: 500 mg / day in 2 doses.
otitis:
Adults: 500 mg / day in 2 doses.
Children over 5 years 30 mg / kg / day in 2 divided doses not to exceed the adult dose, 500 mg / day in 2 doses.
Lower respiratory tract infections:
- Acute or chronic bronchitis:
Adult: 500 mg / day in 2 doses.
- Bacterial Pneumonia:
Adult: 1000 mg / day in 2 doses.
The recommended dosage is to take 2 doses 12 hours apart, about 15 to 30 minutes after meals in the morning and evening.
In renal failure: When the creatinine clearance less than 20 ml / min, reduce the dose by half in a single oral daily dose.
A dd an extra dose at each end of dialysis patients dialyzed chronic.

Store at a temperature below 30oC.

 

Registration no.: 045L-09