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KETALGIC 100 Cp.

B / 30Cp / 3BL
€3.16

COMPOSITION
- Ketoprofen (DCI) 100 mg

INDICATIONS
They are limited in adults and children 15 years at:
Symptomatic long-term treatment:
• chronic inflammatory arthritis, including rheumatoid arthritis, ankylosing spondylitis (or related syndromes, such as syndrome Fiessinger Reiter and psoriatic arthritis);
• some painful and debilitating arthritis.
Symptomatic short-term treatment of acute attacks:
• abarticular such as rheumatism périarhrites scapulohumérales, tendonitis, bursitis;
• microcrystalline arthritis;
• osteoarthritis;
• low back pain;
• nerve root;
• benign post-traumatic acute musculoskeletal.

CONTRAINDICATIONS
• Hypersensitivity to ketoprofen or any of the excipients.
• Beyond 24 weeks of gestation (5 months of age pregnancy)
• History of asthma triggered by taking ketoprofen or substances of close activity as other NSAIDs, aspirin.
• gastrointestinal bleeding, cerebrovascular bleeding or other bleeding evolving.
• gastric or intestinal ulcer disease.
• Severe hepatic impairment.
• Severe renal impairment.
• uncontrolled severe heart failure.
• Pregnant woman from the 6th month and lactation.

DRUG INTERACTIONS
• Combinations not recommended:
   - Oral anticoagulants,
- Other NSAIDs including salicylate from 3 g / day
- Heparin, lithium, methotrexate (used in excess or equal to 15mg doses per week), Ticlopidine.
• Association requiring precautions for use:
Diuretics, methotrexate (used at lower doses to 15 mg per week), pentoxifylline, Zidovudine.
• To be taken into account:
   Beta blockers, cyclosporin and Thrombolytic.

WARNINGS AND PRECAUTIONS
• Patients with asthma associated chronic rhinitis, chronic sinusitis and / or nasal polyposis, have a risk of an allergic reaction, when taking aspirin and / or anti-inflammatory drugs, more higher than the rest of the population.
• As with other NSAIDs, ketoprofen may mask signs of progression from infection.
• The Ketoprofen should be administered with caution and under special surveillance in patients with a history of gastrointestinal (peptic ulcer, ulcerative colitis, Crohn's disease).
• In patients with disturbed liver function tests or a history of liver disease, monitoring of transaminases is recommended.
• During prolonged treatment, it is recommended to monitor blood counts, liver and renal function.
Warn patients of the possible occurrence of dizziness drowsiness, seizures or visual disturbances. It is advisable not to drive or operate machinery if any of these symptoms occur.
Can cause:
• Gastrointestinal: nausea, vomiting, diarrhea, constipation, gastrointestinal discomfort and stomach pain, gastritis, stomatitis, rarely colitis. The most serious adverse reactions are peptic ulcer disease, gastrointestinal bleeding and intestinal perforations.
• Hypersensitivity reactions:
• Very rare cases of angioneurotic edema and anaphylactic shock;
• Skin: rash, rash, pruritus, urticaria, aggravation of chronic urticaria;
• Breathing: possible occurrence of an asthma attack or bronchospasm, especially in subjects allergic to aspirin and other

 

NSAIDs.
• neuropsychiatric disorders: headache, dizziness, drowsiness,
• Eye Trouble: blurred vision
• Hearing Disorders: tinnitus
• Renal: acute renal failure
• Hepatic: increased levels of transaminases
• Heart disease: hypertension
• Other disorders: edema.

DOSAGE AND ADMINISTRATION
• Symptomatic treatment in the long term: 200mg daily or 1-2 tablets of 100 mg / day.
• Symptomatic treatment of acute exacerbations of short duration: 300mg per day or 3 tablets of 100 mg / day.
Frequency of administration:
The daily dosage is from 1-3 in a day.
Renal impairment and elderly: it is recommended to reduce the starting dose and if necessary to adapt this one based on the renal tolerance.

Store at a temperature below 30.degree.

 

Registration no.: 08L-570