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CLARICIN-MS 250 Cp.

B / 40Cp / 4BL
€10.27

COMPOSITION
Clarithromycin (DCI) ................................... 250mg

INDICATIONS
They are limited in adults with infections caused by germs identified as sensitive, including:
- Tonsillitis and pharyngitis,
- Acute sinusitis,
- Acute bronchial fistulae,
- Secondary infections of chronic bronchitis,
- Acute pneumonia,
- Benign skin infections.
Curative treatment of Mycobacterium avium in patients infected with HIV (+).

CONTRAINDICATIONS
- Allergy to macrolides.
- Alkaloids of vasoconstrictor ergot (ergotamine and dihydroergotamine) and terfenadine.
- Pregnancy and lactation.
- Bromocriptine and triazolam.

WARNINGS AND PRECAUTIONS
In the treatment of Mycobacterium avium infections in HIV (+) patients, and to limit the emergence of resistant strains, clarithromycin should be used:
- In combination with other antibiotics, not alone,
- In case of severe hepatic impairment. If it is needed, then it warrants regular monitoring liver function tests.
- In patients with renal insufficiency, longer made, a reduction in dosage.
- In patients older.
Can cause:
- Gastrointestinal events: nausea, vomiting, stomach pains, diarrhea.
- Skin Allergic reactions.
- Increases skin allergies.

DOSAGE AND ADMINISTRATION
adult:
- Tonsillitis, pharyngitis and mild skin infections:
   500mg / d or 2 tablets morning and either
- Acute sinusitis and pneumonia:
   1000mg / d or 4 tablets morning and night.
- Bronchial Infections:
   500mg and 1000mg / d depending on the severity.
- Infections with Mycobacterium avium in HIV (+) patients:
• 2000mg / day in subjects> 50 kg
• 1500mg / day in subjects ≤ 50kg
Renal impairment:
• For values of creatinine clearance <30 ml / min, it may be advisable to reduce the dosage in half with a single daily administration.
In Mycobacterium avium, it is recommended to use a dose of 1000 mg / d.
Elderly
When renal function is markedly reduced, it may be prudent to reduce the dosage.

Store at a temperature below 30.degree.

 

Registration no.: 08L-416