Cimetidine ................................................. .................... 400 mg
- Active gastric or duodenal ulcer in adults.
- Maintenance treatment of duodenal ulcer, in patients not infected with Helicobacter pylori eradication or who has not been possible.
- Treatment of esophagitis secondary to gastroesophageal reflux
- Zollinger-Ellison syndrome.
Absolute: Known hypersensitivity to cimetidine.
Relative: carmustine, lomustine, phenytoin.
Pregnancy and lactation.
WARNINGS AND PRECAUTIONS
- The administration of acid suppressing the class of H2 antagonists promotes bacterial growth by intragastric déminution gastric acidity.
- Cimetidine can only be prescribed if the ulcer was authenticated by endoscopy.
- In gastric ulcer cases it is advisable to check the benignity of the lesion before treatment.
- Cimet 400mg is not suitable for treating renal failure, children, or in patients with severe hepatic impairment.
- In the elderly, it is best to avoid the single dose of 800mg of CIMET day.
Diarrhea, fatigue, headache, feverish conditions, muscle aches, dizziness, rash sometimes severe have been reported.
For adults only
• Treatment of peptic ulcer disease: the dose is:
- Either 400mg at breakfast and 400mg at bedtime;
- Either of 800mg at bedtime.
Treatment should be continued 4-6 weeks, although symptomatic improvement was observed before that time.
• Maintenance treatment of duodenal ulcer: if treatment is warranted, the dosage is 400 mg daily at bedtime.
• Treatment of esophagitis: the daily dose is 800 mg to 1.6 g depending on the severity of the lesions.
• Treatment should be continued 4-8 weeks, although symptomatic improvement was observed during this period, and may possibly be continued until 12 weeks.
• Treatment of Zollinger-Ellison syndrome: the dose may be increased if necessary up to 2g per day.
The tablets should be swallowed with a little water.
Registration no.: 09L-693