B / 100Cp / 10BL

      Cimetidine ................................................. .................... 400 mg

- Active gastric or duodenal ulcer in adults.
- Maintenance treatment of duodenal ulcer, in patients not infected with Helicobacter pylori eradication or who has not been possible.
- Treatment of esophagitis secondary to gastroesophageal reflux
- Zollinger-Ellison syndrome.

Absolute: Known hypersensitivity to cimetidine.
Relative: carmustine, lomustine, phenytoin.
Pregnancy and lactation.

- The administration of acid suppressing the class of H2 antagonists promotes bacterial growth by intragastric déminution gastric acidity.
- Cimetidine can only be prescribed if the ulcer was authenticated by endoscopy.
- In gastric ulcer cases it is advisable to check the benignity of the lesion before treatment.
- Cimet 400mg is not suitable for treating renal failure, children, or in patients with severe hepatic impairment.
- In the elderly, it is best to avoid the single dose of 800mg of CIMET day.
Can cause:
Diarrhea, fatigue, headache, feverish conditions, muscle aches, dizziness, rash sometimes severe have been reported.

For adults only
• Treatment of peptic ulcer disease: the dose is:
- Either 400mg at breakfast and 400mg at bedtime;
- Either of 800mg at bedtime.
Treatment should be continued 4-6 weeks, although symptomatic improvement was observed before that time.
• Maintenance treatment of duodenal ulcer: if treatment is warranted, the dosage is 400 mg daily at bedtime.
• Treatment of esophagitis: the daily dose is 800 mg to 1.6 g depending on the severity of the lesions.
• Treatment should be continued 4-8 weeks, although symptomatic improvement was observed during this period, and may possibly be continued until 12 weeks.
• Treatment of Zollinger-Ellison syndrome: the dose may be increased if necessary up to 2g per day.

The tablets should be swallowed with a little water.


Registration no.: 09L-693